Treatment Cases

Resting State Functional Connectivity After Sphenopalatine Ganglion Blocks in Chronic Migraine With Medication Overuse Headache: A Pilot Longitudinal fMRI Study Kaitlin Krebs, MSc; Chris Rorden, PhD; X. Michelle Androulakis, MD, MSc Objective In this pilot study, the purpose is to investigate if a series of sphenopalatine ganglion (SPG) blockade treatments modulate the functional connectivity within the salience and […]

Hemicrania Continua May Respond to Repetitive Sphenopalatine Ganglion Block: A Case Report Michelle Androulakis, MD, MSc; Kaitlin A. Krebs, BA; Avi Ashkenazi, MD Background Hemicrania continua (HC) is a chronic headache disorder characterized by a continuous, strictly unilateral head pain accompanied by cranial autonomic symptoms, which completely responds to indomethacin; however, few alternative treatment options

Long‐Term Efficacy of a Double‐Blind, Placebo‐Controlled, Randomized Study for Repetitive Sphenopalatine Blockade With Bupivacaine vs Saline With the Tx360® Device for Treatment of Chronic Migraine Roger K. Cady, MD; Joel Saper, MD; Kent Dexter, MD; Ryan J. Cady, MS; Heather R. Manley, MS, LPC Background This study aims to determine if repetitive sphenopalatine ganglion (SPG)

A Double-Blind, Placebo-Controlled Study of Repetitive Transnasal Sphenopalatine Ganglion Blockade With Tx360® as Acute Treatment for Chronic Migraine Roger Cady, MD; Joel Saper, MD; Kent Dexter, MD; Heather R. Manley, MS, LPC Objective To determine if repetitive sphenopalatine ganglion (SPG) blocks with 0.5% bupivacaine delivered through the Tx360® are superior in reducing pain associated with

A Novel Revision to the Classical Transnasal Topical Sphenopalatine Ganglion Block for the Treatment of Headache and Facial Pain Kenneth D. Candido, MD, Scott T Massey, MD, Ruben Sauer, MD, Raheleh Rahimi Darabad, MD, and Nebojsa Nick Knezevic, MD, PhD. Background The sphenopalatine ganglion (SPG) is located with some degree of variability near the tail

Cortical and Subcortical Changes Following Sphenopalatine Ganglion Blocks In Chronic Migraine With Medication Overuse Headache: A Preliminary Longitudinal Study Roger D. Newman-Norlund1* , Chris Rorden1, Nasim Maleki2, Milap Patel3, Brian Cheng3 and X. Michelle Androulakis3,4 Objective The purpose of this pilot study was to investigate potential changes in brain morphology (cortical thickness and cortical/subcortical volume) accompanying